PED-ENDOCRINOLOGY BASIC RES (IN-PENB-IUINA)
The Herman B Wells Center for Pediatric Research conducts basic science and translational research within the Department of Pediatrics at Indiana University School of Medicine. The Wells Center houses more than 200 faculty investigators, staff and trainees seeking answers to the most pressing questions related to childhood illness.
With the collaboration between scientists and physicians, the center aims to increase knowledge of causes and mechanisms of serious pediatric diseases. Our goal is to develop innovative approaches to the diagnosis and treatment of sick children in Indiana and beyond.
The Wells Center encompasses a breadth of multidisciplinary expertise in biochemistry and molecular biology, immunology, molecular genetics, and cellular and integrative physiology—making it a uniquely collaborative environment.
This position will assist the Principal Investigator in conducting research in Diabetes Research Group within the Wells Center for Pediatric Research. This research is focused on examining the role of microRNAs in the regulation of intrinsic beta cell stress pathways during diabetes development. This research makes extensive use of molecular biology techniques. This research includes small animal handling, small animal surgery, and molecular, cellular biology and biochemistry experiments.
Primary Duties and Responsibilities:
- Maintain mouse colonies. Consists of setting up and maintaining breeder cages, maintaining non-breeding cages, animal handling, such as weaning, ear notching, tail snips, dosing, and maintaining colony records.
- Perform molecular biology experiments including, but not limited to, intraperitoneal glucose tolerance tests (IPGTTs), ELISAs, islet isolation, immunoblot and staining, RNA sequencing, tissue culture, Glucose Stimulated Insulin Secretion assays, Luciferase assays, immunohistochemistry, genotyping, western blot analysis and qRT-PCR assays.
- General laboratory management duties, including order lab supplies, maintain inventory and reagents, assist with the maintenance of regulatory monitoring and paperwork (IACUC, IRB, Biosafety, Laboratory Safety, and Radiation Safety), set-up and maintenance of laboratory equipment, and schedule laboratory meetings and presentations, as needed.
Bachelor's degree in science.
Hands-on laboratory experience and the ability to learn quickly. Ability to function independently and conduct experiments. Experience in mouse and small animal colony maintenance and/or small animal surgery. Ability to problem solve.
One year of lab experience.
Salary Plan: RS
Salary Grade: 07
Job Function: Research
Due to the COVID-19 pandemic, there may be differences in the working conditions as advertised in our standard job postings (e.g., the ability to travel from one campus to another, etc.). If you are invited for an interview, please discuss your questions or concerns regarding the working conditions at that time.
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